Picture shows clinical features-
1. Nasal or oral inflammation: painless or painful oral ulcers or purulent or bloody nasal discharge
2.Abnormal chest radiograph: presence of nodules, fixed infiltrates or cavities
3.Urinary sediment: microhematuria (> 5 red blood cells per high power field) or red cell casts in urine sediment.
4.Granulmatous inflammation on biopsy: granulomatous inflammation within the wall of an artery or in the perivascular or extravascular area (artery or arteriole)
Requirements: ≥ 2 of the above 4 criteria are required for classification as GPA. Sensitivity 88.2%, specificity 92.0%.
The American College of Rheumatology 1990 criteria for the classification of Wegener’s Granulomatosis.